FATCELL®

Stem Cell Therapy resulting from fat

Complex stem cell suspension which is isolated from abdominal fat tissue, usually in the laboratory environment under GMP conditions, manually by bioengineering techniques. These fat stem cells are also called Stromal Vascular Fraction (SVF).These adipose-derived and regenerative cells; Multipotent progenitors (adipose tissue-derived stem cells), mesenchymal stem cells (regenerative cells), endothelial progenitor cells, and vascular smooth muscle cells.
The presence of many different stem cell sources and active biomolecules in the SVF has opened up the possibility that it can be used in many different health problems and has been more advantageous compared to stem cell sources such as bone marrow and cord blood.

Many stem cells, mainly mesenchymal stem cells, within the SVF have specific tissue-specific differentiation capacity and can repair tissue by converting into adipocytes, chondrocytes, osteoblasts, hepatocytes, cardiomyocytes, neron cells, epithelial cells and endothelial cells.
SVF provides oxygen and nutrient transport to the region where it is injected and activates repair mechanisms by increasing the angiogenesis (vascular formation) by containing many growth factors (EGF, VEGF, bFGF) and active biomolecules as well as rich variety of stem cells.
When SVF provided with systemic circulation, can regulate protein structures that regulate the inter-endothelial cell signaling, vascular flexibility and permeability.

Despite the fact that Fat Grafting has been discovered in the 19th century and is now widely used in aesthetic operations, obtained from adipose tissue stem cells (SVF) has gained value in recent years and has become a more advantageous method of cellular therapy than bone marrow and cord blood.

Advantages

  • Allergic side effects are not expected because it is obtained from its own fat tissue.
  • It contains a rich variety of stem cells at least 3 times more than bone marrow and cord blood thereby increasing the effectiveness of the treatment.
  • Fat tissue ingestion occurs more easily than bone marrow.
  • Cultivation and treatment will be carried out within 48 hours without the need for weeks of waiting.
  • On the one hand, the patient gets rid of unwanted fat in the abdominal or basal area, and on the other hand he gets the treatment he needs.
  • Because it contains a rich variety of stem cell populations, it can be used in many different diseases.
  • It is not toxic, it does not contain synthetic ingredients.
  • Results are fast and long lasting.
  • It does not contain animal (cattle, pig) components.

Areas of use

  • In the treatment of festering chronic sores (diabetes, compression, venous ulcer, polyarteritis nodosa, etc.)
  • In erectile dysfunction (impotence),
  • In neurodegenerative diseases (MS, Alzheimer, ALS, Parkinson, SMA, Autism),
  • In anti-aging applications,
  • Breast augmentation, penis and vaginal aesthetics, strengthening of the pelvic muscles,
  • In the aesthetic therapy areas such as baldness therapy and rhytid etc,
  • In autoimmune diseases,
  • In the treatment of Type-1 and Type-2 diabetes,
  • In joint, cartilage worn, meniscus, tendon and connective tissue injuries,
  • In osteoarthritis, chronic wrist twists,
  • In unfamiliar fracture treatments, in waist treatment, in degenerative cartilage diseases, in disc degeneration between vertebrae,
  • In the filling of the pits that occur after disturbances such as acne or varicella,
  • In the treatment of burns, past surgery or trauma-related cavities and nevas,
  • In filling the lips
  • In periodontal applications, in implant applications,
  • In degenerative diseases of the movement system,
  • for muscle rupture.

*The multi-functionality of the root cell (SVF) from the oven has the advantage of being used in many different indications. However, it should be known that the person’s condition, age, disease course, genetic predisposition, and many other factors will affect the success of this treatment so the application decision should be made as a result of doctor evaluation.

SVF STEM CELL TRANSPLANTATION PROCEDURE

Examination:  The patient is examined by the physician. The diagnosis of the illness, the condition of the patient, the complaints and all the reports and results are evaluated. The amount of the fat to be bought and the application frequency are determined. The patient is informed fully and completely at the expected benefit point after application and after the need. The operation appointment is taken.

Lipoaspirate Procedure: From the patient, It is taken by the plastic surgeon under appropriate conditions, preferably in the abdomen. This procedure is painless under local anesthesia. Received fat are placed in special sterile tissue containers and transferred to the DOKU LAB in the cold chain.

Preparation of SVF stem cells:  The tissue that reaches the laboratory is processed by the expert biologists and bioengineers in the clean room system of the GMP standards, and the stem cells are separated. The SVF cells that pass through the required quality control tests are packaged sterile and transferred into the cold chain to be transferred to the clinic / hospital. * SVF stem cells are isolated and inspected by bioengineering specialists in the GMP standard laboratory environment and subjected to quality control tests. These isolation procedures should not be confused with clinical, hospital, or automated device-based procedures, stem cell extraction procedures of unknown quality and safety.

Application:The patient is prepared for the operation. SVF stem cell administration is performed by selecting the appropriate injection method (intradermal, intramuscular, etc.), according to the diagnosis of the disease. The patient does not feel pain during this operation. The affected area is numbed with local anesthetics. After the operation, it is usually sufficient for the patient to rest for 1-2 hours, but depending on the situation, it may be necessary to keep it under observation for 24 hours. After the rest, the patient is sent home if there is no other incident.

Control: Intermediate controls are planned between the physician and the patient and the healing process is followed.

Brochure & Link

Click for the FATCELL® brochure.(Türkçe)(English)

Scientific Studies
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